Good-bye CRRT, here comes SLED? ... not so fast!
نویسنده
چکیده
In the continuing dispute about the superiority of either intermittent or continuous renal replacement therapy for the critically ill, hybrid methods such as sustained low-efficiency dialysis (SLED) combining the advantages of both modalities--that is, excellent hemodynamic stability and low costs--receive growing attention. The study by Schwenger and colleagues is the first randomized trial indicating that there may be no significant difference in survival at 90 days between patients treated with SLED as compared with those treated with continuous veno-venous hemofiltration.
منابع مشابه
Outcomes of sustained low efficiency dialysis versus continuous renal replacement therapy in critically ill adults with acute kidney injury: a cohort study
BACKGROUND Sustained low efficiency dialysis (SLED) is increasingly used as a renal replacement modality in critically ill patients with acute kidney injury (AKI) and hemodynamic instability. SLED may reduce the hemodynamic perturbations of intermittent hemodialysis, while obviating the resource demands of CRRT. Although SLED is being increasingly used, few studies have evaluated its impact on ...
متن کاملThe hemodynamic tolerability and feasibility of sustained low efficiency dialysis in the management of critically ill patients with acute kidney injury
BACKGROUND Minimization of hemodynamic instability during renal replacement therapy (RRT) in patients with acute kidney injury (AKI) is often challenging. We examined the relative hemodynamic tolerability of sustained low efficiency dialysis (SLED) and continuous renal replacement therapy (CRRT) in critically ill patients with AKI. We also compared the feasibility of SLED administration with th...
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Doripenem is a novel wide-spectrum antibiotic, and a derivate of carbapenems. It is an ideal antibiotic for treatment of serious nosocomial infections and severe sepsis for its exceptionally high efficiency and broad antibacterial spectrum of action. Doripenem is eliminated mainly by the kidneys. In cases of acute kidney injury, dosing of doripenem depends on creatinine clearance and requires a...
متن کاملComparison between sustained low-efficiencydialysis (SLED) and continuous renal replacement therapy (CRRT) in patients of septic shock: a randomized controlled trial
Methods Prospective randomized study in a 12 bedded medical ICU. After clearance from institutes ethics committee and taking informed consent from the relatives 40 adult patients in septic shock who were to undergo dialysis for Acute Kidney Injury were included in the study. They were randomly assigned to SLED or CRRT group. They underwent the same modality of dialysis until they were hemodynam...
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New storage devices based on Micro-Electro-Mechanical Systems (MEMS) have been proposed [3]. Enabled by high storage densities (> 1 Tb/in), MEMS technology promises to deliver small-form factor, high-capacity, and low-power storage devices. These devices have potentially low cost, because they can be manufactured using batch MEMS fabrication technology. A MEMS-based storage device dissipates an...
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عنوان ژورنال:
دوره 16 شماره
صفحات -
تاریخ انتشار 2012